KMID : 0363320190400040723
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Journal of Korean Oriental Internal Medicine 2019 Volume.40 No. 4 p.723 ~ p.729
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A Case of Long-term Survival with Traditional Korean Medicine Alone for Recurrent Metastases of Colorectal Cancer
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Kim Eun-Hye
Yoon Sung-Soo Lee Ji-Young Yun Seong-Woo
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Abstract
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Objective: This study was aimed at reporting on a patient with repeated recurrence of metastatic colorectal cancer treated with traditional Korean medicine (TKM) alone after operation and chemotherapy.
Method: The patient with metastatic colorectal cancer received tumor resections four times and perioperative chemotherapy for repeated recurrence from February 2013 until March 2015. TKM, which included Gunchil-dan and Haeam-dan, was administered until June 2019 to prevent additional relapses.
Results: After 49 months of TKM treatment, there was no tumor recurrence. A no evidence of disease (NED) state was maintained from March 2015 to June 2019. Recurrence-free survival (RFS) was shown for 49 months and overall survival (OS) for 78 months. Serious adverse events evaluated according to the Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0 were not identified. This study suggested that TKM with herbal medicine including aRVS might prolong survival and inhibit recurrence of tumors in patients with metastatic colorectal cancer.
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KEYWORD
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colorectal cancer, recurrence, Gunchil-dan, Haeam-dan, traditional Korean medicine, herbal medicine
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